Method for producing 4-[2',5'-diamino-6'-halopyrimidine-4'-yl)amino]- cyclopent-2-enylmethanols
US6433170B1 · kind B1 · utility
0Cited by
14References
16Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 17, 2001 |
| Grant date | Aug 13, 2002 |
| Priority date | — |
| Expiry date | Jun 17, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D239/50
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention relates to a novel method for producing 4-[(2′,5′-diamino-6′-halopyrimidine-4′-yl)amino]-cyclopent-2-enylmethanols of general formula (I), wherein X represents a halogen atom. According to the inventive method amino-4,6-halopyrimidine of general formula (II), wherein X has the aforementioned meaning, is reacted with a 4-aminocyclopent-2-enylmethanol of formula (III) or with a salt thereof in the presence of a base in a polar protic solvent.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.