Carboxylic acids for synthesis of taxane derivatives
US6433180B1 · kind B1 · utility
1Cited by
5References
5Claims
0Family size
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Key dates
| Filing date | Aug 8, 1997 |
| Grant date | Aug 13, 2002 |
| Priority date | — |
| Expiry date | Aug 8, 2017 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/55
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Novel carboxylic acids of formula (VI), useful for preparing taxane derivatives of general formula (I) by esterifying protected baccatine (III) or protected diacetyl baccatin (III) with an acid of general formula (II). The products of general formula (I) are particularly useful for preparing taxol, Taxotere and analogs thereof having anti-tumor properties.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.