Human pancreatic epithelial progenitor cells and methods of isolation and use thereof
US6436704B1 · kind B1 · utility
170Cited by
5References
13Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 10, 2000 |
| Grant date | Aug 20, 2002 |
| Priority date | — |
| Expiry date | Apr 10, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2501/60
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention discloses a substantially pure population of human pancreatic progenitor cells and methods of isolating and culturing the pancreatic progenitor cells. By carefully manipulating the microenvironment of the pancreatic progenitor cells, multiple passages are attainable wherein the pancreatic progenitor cells do not senesce and furthermore, are capable of becoming functional exocrine or endocrine cells. In addition, several methods of use of human pancreatic progenitor cells are disclosed herein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.