Indane or dihydroindole derivatives
US6436940B1 · kind B1 · utility
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2References
19Claims
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Assignee
Inventors
Key dates
| Filing date | Jul 26, 2001 |
| Grant date | Aug 20, 2002 |
| Priority date | — |
| Expiry date | Jul 26, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D317/66
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to substituted indane or dihydroindole compounds of Formula (I),wherein A and B are independently O or S; D is an optionally substituted methylene group; X is N or optionally substituted C; and W is a spacer group. The compounds are either selective dopamine D4 ligands or they have combined effects at dopamine D4 and serotonergic receptors and/or the serotonergic transporter. These compounds are therefore useful in the treatment of certain psychiatric and neurologic disorders, including psychosis, depression and anxiety.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.