Pharmaceutical agents for the treatment of emesis
US6436961B1 · kind B1 · utility
11Cited by
46References
7Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 18, 1995 |
| Grant date | Aug 20, 2002 |
| Priority date | — |
| Expiry date | Sep 18, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D211/56
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to a novel process for preparing and resolving 3-amino-2-phenylpiperidine and for synthesizing from the enantiomers of such compound certain pharmaceutically active substituted 2-phenyl-3-benzylaminopiperidines. The substituted 2-phenyl-3-benzylaminopiperidines that can be prepared by the processes of this invention are substance P receptor antagonists and are useful in the treatment and prevention of inflammatory and central nervous system disorders, as well as several other disorders.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.