Methods and compositions for the manufacture of highly potent anthracycline-based antitumor agents
US6437105B1 · kind B1 · utility
4Cited by
4References
15Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 2, 1999 |
| Grant date | Aug 20, 2002 |
| Priority date | — |
| Expiry date | Nov 2, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H15/252
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention discloses new and novel substituted anthracyclines having a three ring system or other DNA binding moieties. These congeners show high activity in vitro against several tumor cell lines. The invention also describes anthracycline-based DNA alkylators.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.