Process for preparing retiferol derivatives
US6437142B1 · kind B1 · utility
2Cited by
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4Claims
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Key dates
| Filing date | Mar 26, 2001 |
| Grant date | Aug 20, 2002 |
| Priority date | — |
| Expiry date | Mar 26, 2021 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/582
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A new process prepares retiferol derivatives of formula I: whereinA is —C≡C— or —CH═CH—, andR1 and R2 are independently of each other lower alkyl or lower perfluoroalkyl,one version couples ketones of formula II with compounds of formula III. A second version couples phosphinoxides of formula IV with aldehydes of formula V. Compounds of formula I are useful in the treatment or prevention of hyperproliferative skin diseases and for reversing the conditions associated with photodamage.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.