Erythromycins and process for their preparation
US6437151B2 · kind B2 · utility
11Cited by
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10Claims
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Key dates
| Filing date | Jun 29, 2001 |
| Grant date | Aug 20, 2002 |
| Priority date | — |
| Expiry date | Jun 29, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/00
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Erythromycins, particularly ones with novel C-13 substituents R1 (e.g. C3-C6 cycloalkyl or cycloalkenyl groups) are prepared by fermenting suitable organisms in the presence of R1CO2H. A preferred organism is Saccharopolyspora erythraea preferably containing an integrated plasmid capable of directing synthesis of desired compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.