Method for producing (S,S)-N,N′-ethylenediaminedisuccinic acid, analogous compounds or salts thereof

US6437181B1 · kind B1 · utility

Assignee

• BASF SE

Inventors

• Alfred Oftring · Bad Dürkheim, DE
• Christian Ott · Speyer, DE
• Birgit Potthoff-Karl · Weinheim, DE

Key dates

• Filing date: Nov 27, 2000
• Grant date: Aug 20, 2002
• Expiry date: Nov 27, 2020

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C227/18
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention describes a process for the preparation of (S,S)-N,N′-ethylenediaminedisuccinic acid or analogous compounds or their salts by reaction of L-aspartic acid, L-glutamic acid or L-cysteic acid with 1,2-bissulfooxyethane, 1,3,2-dioxathiolane 2,2-dioxide or mixtures thereof or 1,3-bissulfooxy-2-hydroxypropane in the presence of a base, and optional subsequent acidification with an acid.Also described is a process for the preparation of (S,S)-N,N′-ethylenediaminedisuccinic acid or analogous compounds or their salts by reaction of N-(2-sulfooxyethyl)-L-aspartic acid or its salts with L-aspartic acid or corresponding compounds based on L-glutamic acid, L-cysteic acid and/or 1,3-bissulfooxy-2-hydroxypropane in the presence of a base, and optional subsequent acidification with an acid.