Remineralizing-mineralizing oral products containing discrete cationic and anionic agglomerate components and method of use
US6440394B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jun 26, 2001 |
| Grant date | Aug 27, 2002 |
| Priority date | — |
| Expiry date | Jun 26, 2021 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2800/88
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A solid oral product, e.g., chewing gum, lozenge, an edible foodstuff, and the like, which is useful for remineralizing subsurface dental lesions and/or mineralizing exposed dentinal tubules, contains (A) a discrete cationic agglomerate component composed of at least one water-soluble or partially water-soluble calcium salt and a first inert solid carrier, and (B) a discrete anionic agglomerate component composed of at least one water-soluble orthophosphate salt and a second inert solid carrier. The agglomerate nature of the cationic and anionic components keeps these components separate from one another during storage of the product but allows the cationic and anionic salts to be simultaneously released from the product upon mixing of the product with water and/or saliva to form a mixed aqueous solution such that the solution contains both calcium cations released from the calcium salt and orthophosphate anions released by the orthophosphate salt.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.