Poly(methylidene malonate) microspheres, preparation method and pharmaceutical compositions containing them
US6440461B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Dec 19, 2000 |
| Grant date | Aug 27, 2002 |
| Priority date | — |
| Expiry date | Dec 19, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08J2335/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention concerns novel microspheres particularly useful in pharmaceutics as particulate vectors for carrying biologically active substances, in particular hydrophilic substances, for oral administration. The invention is characterised in that said microspheres consist of a support material continuous lattice wherein is optionally dispersed a substance, said support material containing at least 70 wt. % of a homopolymer consisting of recurrent units corresponding to general formula (I): wherein: R1 represents an alkyl group containing 1 to 6 carbon atoms or a (CH2)m—COOR3 group wherein m is an integer ranging between 1 and 5 and R3 represents an alkyl group having 1 to 6 carbon atoms; R2 represents an alkyl group having 1 to 6 carbon atoms; and n is an integer ranging between 1 and 5. The invention is useful in pharmaceutics.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.