Dipeptide benzamidine as a kininogenase inhibitor

US6440937B1 · kind B1 · utility

Assignee

• Abbott Laboratories · US

Inventors

• Dorit Baucke · Mannheim, DE
• Udo Lange · Ludwigshafen, DE
• Helmut Mack · Ludwigshafen, DE
• Thomas Pfeiffer · Kumhausen, DE
• Werner Seitz · Plankstadt, DE
• Thomas Zierke · Böhl-Iggelheim, DE
• Hans Wolfgang Höffken · Ludwigshafen, DE
• Wilfried Hornberger · Wiesbaden, DE

Key dates

• Filing date: Feb 10, 1999
• Grant date: Aug 27, 2002
• Expiry date: Feb 10, 2019

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02P20/55
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Compounds of the formula I where R, R1, R2, R3, R4, R5 and R6, and l, m and n have the meanings stated in the description, and their preparation are described. The novel compounds are suitable for controlling diseases.