Water soluble paclitaxel derivatives
US6441025B2 · kind B2 · utility
43Cited by
34References
25Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 30, 1998 |
| Grant date | Aug 27, 2002 |
| Priority date | — |
| Expiry date | Mar 30, 2018 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L2300/606
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed are water soluble compositions of paclitaxel and docetaxel formed by conjugating the paclitaxel or docetaxel to a water soluble polymer such as poly-glutamic acid, poly-aspartic acid or poly-lysine. Also disclosed are methods of using the compositions for treatment of tumors, auto-immune disorders such as rheumatoid arthritis. Other embodiments include the coating of implantable stents for prevention of restenosis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.