Production of motif-specific and context-independent antibodies using peptide libraries as antigens
US6441140B1 · kind B1 · utility
38Cited by
1References
5Claims
0Family size
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Key dates
| Filing date | Sep 4, 1998 |
| Grant date | Aug 27, 2002 |
| Priority date | — |
| Expiry date | Sep 4, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K16/44
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention is related to a method for producing motif-specific, context-independent antibodies which are specific to at least one modified fixed amino acid residue in the context of variable surrounding amino acid or peptide sequences. The method is particularly useful in producing antibodies which recognize phosphorylated serine, threonine, and tyrosine, or acetylated lysine, as well as other modified amino acid-containing motifs of one or more amino acids.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.