Method for the production of 4,6-dichloropyrimidine with the aid of phosgene

US6441171B1 · kind B1 · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Franz-Josef Mais · Düsseldorf, DE
• Gunther Cramm · Leverkusen, DE
• Alexander Klausener · Neunburg vorm Wald, DE
• Guido Steffan · Odenthal, DE

Key dates

• Filing date: Jan 24, 2002
• Grant date: Aug 27, 2002
• Expiry date: Jan 24, 2022

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D237/12
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention relates to a method for the preparation of 4,6-dichloropyrimidine by reacting 4-chloro-6-methoxypyrimidine with phosgene as chlorinating agent in the presence of a nitrogen-containing auxiliary.