Patent · US Expired

Medication device with protein stabilizing surface coating

US6443942B1 · kind B1 · utility

200Cited by
43References
20Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 6, 2001
Grant dateSep 3, 2002
Priority date
Expiry dateJun 6, 2021

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10T428/31855
  • WIPO fieldMedical technology
  • WIPO sectorInstruments

Abstract

The present invention provides medical devices such as medication infusion pumps having internal surfaces that are treated to inhibit protein denaturation. In accordance with the invention, hydrophilic internal surfaces and related coating methods are provided to reduce or eliminate accumulation of medication deposits which can otherwise occur when handling complex protein-based medications. Preferred hydrophilic pump surfaces include hydrophilic surfactants (PEO) or (PEG) coatings which exhibit very low protein adsorption characteristics. Several methods are disclosed for producing such treated surfaces including the covalent attachment of hydrophilic surfactants.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.