Calcium binding proteolipid compositions and methods
US6444446B1 · kind B1 · utility
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10Claims
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Key dates
| Filing date | Nov 23, 1999 |
| Grant date | Sep 3, 2002 |
| Priority date | — |
| Expiry date | Nov 23, 2019 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K39/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to the cloning and sequencing of the DNA encoding a membrane associated proteolipid from C. matruchotii that is capable of inducing in vitro calcium binding. A proteolipid was extracted from cultures of C. matruchotii and separated into a lipid component and three apoproteins having molecular weights of approximately 5.0, 5.5 and 7.5 kDa as determined by SDS-PAGE. The invention also includes the polyclonal and monoclonal antibodies directed against the membrane associated proteolipid and immunological assays developed with these antibodies.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.