Synthetic compounds for treatment of inflammation

US6444697B2 · kind B2 · utility

Assignees

• Harbor Branch Oceanographic Institution, Inc. · US
• The Regents of the University of California · US

Inventors

• Amy E. Wright · Fort Pierce, US
• Ralph-Heiko Mattern · Ramona, US
• Robert S. Jacobs · Lompoc, US

Key dates

• Filing date: Jul 27, 2001
• Grant date: Sep 3, 2002
• Expiry date: Jul 27, 2021

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D209/14
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Novel uses of biologically active bis-heterocyclic e.g. bis-indole alkaloid compounds which have improved activity are disclosed. Pharmaceutical compositions containing the compounds are also disclosed. Specifically, the novel Utility pertains to the anti-immunogenic and neurogenic inflammatory properties exhibited by the bis-indole compounds and their analogs.