Conjugates and methods of forming conjugates of oligonucleotides and carbohydrates
US6444806B1 · kind B1 · utility
67Cited by
2References
50Claims
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Key dates
| Filing date | Apr 22, 1997 |
| Grant date | Sep 3, 2002 |
| Priority date | — |
| Expiry date | Apr 22, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2310/351
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Oligonucleotides conjugated to carbohydrates and methods for their production are described. These oligonucleotide-carbohydrate conjugates are resistant to degradation by nucleases, are able to form stable duplexes with RNA, and have utility as inhibitors of gene expression.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.