Pyrazinones, compositions containing such compounds and methods of use
US6444811B1 · kind B1 · utility
2Cited by
2References
1Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 19, 2000 |
| Grant date | Sep 3, 2002 |
| Priority date | — |
| Expiry date | Jul 19, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D417/12
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds represented by formula I: as well as pharmaceutically acceptable salts, esters, N-oxides and hydrates thereof are disclosed. Pharmaceutical compositions and methods of use are also included. The compounds are active against the caspase-3 enzyme, and thus are useful to treat fin caspase-3 mediated diseases and conditions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.