Non-invasive detection of endothelial dysfunction by blood flow measurement in opposed limbs using tracer injection
US6445945B1 · kind B1 · utility
24Cited by
25References
14Claims
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Key dates
| Filing date | Jun 26, 2000 |
| Grant date | Sep 3, 2002 |
| Priority date | — |
| Expiry date | Aug 1, 2020 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61B5/022
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
Endothelial dysfunction is a known indicator of cornary artery disease. Endothelial dysfunction is detected by measuring tracer presence in arteries following the release of blood flow into the limb after a period of blockage of blood flow into the limb. The blood flow is measured in a pair of laterally opposed limbs, such as the patient's forearms, and the tracer presence is compared between both limbs. An efficient tracer is a radionuclide and the non-invasive measurement of the radionuclide is carried out by gamma ray detection.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.