Family of immunoregulators designated leukocyte immunoglobulin-like receptor (LIR)
US6448035B1 · kind B1 · utility
8Cited by
1References
25Claims
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Key dates
| Filing date | Apr 24, 1997 |
| Grant date | Sep 10, 2002 |
| Priority date | — |
| Expiry date | Apr 24, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A new family of immunoreceptor molecules of the immunoglobulin superfamily, (LIR) polypeptides is described. Disclosed are sequences encoding LIR family members and their deduced amino acid sequences, polypeptides encoded by DNA that hybridize to oligonucleotide probes having defined sequences, processes for producing polypeptides of the LIR family, and antagonistic antibodies to LIR family members. LIR family members can be used to treat autoimmune diseases and disease states associated with suppressed immune function.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.