Human cytomegalovirus DNA constructs and uses therefor
US6448389B1 · kind B1 · utility
13Cited by
6References
3Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 19, 1999 |
| Grant date | Sep 10, 2002 |
| Priority date | — |
| Expiry date | Jan 19, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2740/16222
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Novel DNA molecules for in vitro and in vivo expression of HCMV gB, gB transmembrane deleted derivatives, pp65, pp150, and IE-exon-4 proteins are described. Preferably, the molecules are plasmids. Also described are methods of using these DNA molecules to induce immune responses to HCMV, and the use of a plasmid of the invention to prime immune responses to HCMV vaccines.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.