Hydrolytic kinetic resolution of cyclic substrates
US6448414B1 · kind B1 · utility
15Cited by
25References
14Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 5, 2001 |
| Grant date | Sep 10, 2002 |
| Priority date | — |
| Expiry date | Jul 5, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2601/16
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to a process for stereoselective or regioselective chemical synthesis which generally comprises reacting a nucleophile and a chiral or prochiral cyclic substrate in the presence of a non-racemic, chiral catalyst to produce a stereoisomerically- and/or regioisomerically-enriched product. The present invention also relates to hydrolytic kinetic resolutions of racemic and diastereomeric mixtures of epoxides.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.