Multiplexed analysis of clinical specimens apparatus and method
US6449562B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Aug 18, 1998 |
| Grant date | Sep 10, 2002 |
| Priority date | — |
| Expiry date | Aug 18, 2018 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S707/99931
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method for the multiplexed diagnostic and genetic analysis of enzymes, DNA fragments, antibodies, and other biomolecules comprises the steps of constructing an appropriately labeled beadset, exposing the beadset to a clinical sample, and analyzing the combined sample/beadset by flow cytometry is disclosed. Flow cytometric measurements are used to classify, in real-time, beads within an exposed beadset and textual explanations, based on the accumulated data obtained during real-time analysis, are generated for the user. The inventive technology enables the simultaneous, and automated, detection and interpretation of multiple biomolecules or DNA sequences in real-time while also reducing the cost of performing diagnostic and genetic assays.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.