Method for inhibiting an allergic response with a 5c8-specific antibody

US6451310B1 · kind B1 · utility

Assignee

• The Trustees of Columbia University in the City of New York · US

Inventors

• Seth Lederman · New York, US
• Leonard Chess · Scarsdale, US
• Michael J. Yellin · Yonkers, US

Key dates

• Filing date: Jun 7, 1995
• Grant date: Sep 17, 2002
• Expiry date: Jun 7, 2015

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02A50/30
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

This invention provides a method of inhibiting an allergic response in a subject by inhibiting T cell activation of B cells, wherein said method comprises administering to the subject an antibody capable of binding to a protein which is specifically recognized by monoclonal antibody 5C8 produced by the hybridoma having ATCC Accession No. HB 10916.