Methods using genetic package display for selecting internalizing ligands for gene delivery
US6451527B1 · kind B1 · utility
34Cited by
2References
10Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 26, 1999 |
| Grant date | Sep 17, 2002 |
| Priority date | — |
| Expiry date | Feb 26, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2799/021
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A genetic package display system is presented for selecting internalizing ligands for gene delivery. The genetic package carries a reporter, selectable marker, or a specifically detectable nucleic acid sequence and presents a ligand on its surface. More specifically, a library of potential ligands may be screened for the ability to successfully transduce target cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.