4-oxo-3,5-dihydro-4H-pyridazino[4,5-b]indole-1-carboxamide derivatives, preparation and therapeutic use

US6451795B1 · kind B1 · utility

Assignee

• Sanofi-Synthelabo · FR

Inventors

• Frank Marguet · Verrières-le-Buisson, FR
• Jacques Froissant · Châteaudun, FR
• Regine BARTSCH-LI · Fontenay-aux-Roses, FR
• Benoit Marabout · Massy, FR
• Mireille Sevrin · Paris, FR

Key dates

• Filing date: Jul 25, 2001
• Grant date: Sep 17, 2002
• Expiry date: Jul 25, 2021

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

4-Oxo-3,5-dihydro-4H-pyridazino[4,5-b]indole-1-carboxamide derivatives having affinity for the peripheral benzodiazepine receptors are useful for the prevention or treatment of peripheral neuropathies and for the treatment of central neurogenerative diseases.