Patent · US Expired

Fused pyrazine compounds

US6451796B1 · kind B1 · utility

4Cited by
12References
8Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 10, 2000
Grant dateSep 17, 2002
Priority date
Expiry dateMay 10, 2020

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D495/14
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The compound of the formula (I): wherein all the symbols are meaning the same as descriptions of the specification; and salts thereof.The compounds of the formula (I) have inhibitory activity of adhesion molecules expression, and are useful for prevention and/or treatment of inflammation, rheumatoid arthritis, allergies, asthma, atopic dermatitis, psoriasis, suppression of ischemia reperfusion injury, nephritis, hepatitis, multiple sclerosis, ulcerative colitis, adult respiratory distress syndrome (ARDS), suppression of transplant rejection, sepsis, diabetes, autoimmune diseases, tumor metastasis, arteriosclerosis and AIDS.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.