Patent · US Expired

Use of substituted N-phenoxy-N-phenyl aminoalcohol compounds for inhibiting cholesteryl ester transfer protein activity

US6451823B1 · kind B1 · utility

5Cited by
3References
13Claims
0Family size

Assignee

Inventors

Key dates

Filing dateNov 14, 2001
Grant dateSep 17, 2002
Priority date
Expiry dateNov 14, 2021

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07C2603/18
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The invention relates to use of substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamine compounds useful as inhibitors of cholesteryl ester transfer protein (CETP; plasma lipid transfer protein-I) and compounds, compositions and methods for treating atherosclerosis and other coronary artery diseases. Preferred tertiary-heteroalkylamine compounds are substituted N-phenoxy-N-phenyl aminoalcohols. A preferred specific N-phenoxy-N-phenyl aminoalcohol is the compound:

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.