Patent · US Expired

1-(pyrrolidin-1-ylmethyl)-3-(pyrrol-2-ylmethylidene)-2-indolinone derivatives

US6451838B1 · kind B1 · utility

23Cited by
23References
20Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 24, 2001
Grant dateSep 17, 2002
Priority date
Expiry dateMay 24, 2021

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07F9/65583
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention is directed to 1-pyrrolidin-1-ylmethyl-3-(pyrrol-2-ylmethylidene)-2-indolinone derivatives that modulate the activity of protein kinases (“PKs”). Pharmaceutical compositions comprising these compounds, methods of treating diseases related to abnormal PK activity utilizing pharmaceutical compositions comprising these compounds and methods of preparing them are also disclosed.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.