Cyclic amine derivatives and their use as drugs
US6451842B1 · kind B1 · utility
15Cited by
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37Claims
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Key dates
| Filing date | May 16, 2000 |
| Grant date | Sep 17, 2002 |
| Priority date | — |
| Expiry date | May 16, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D495/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A compound represented by the general formula (I), a pharmaceutically acceptable acid addition salt thereof or a pharmaceutically acceptable C1-C6 alkyl addition salt thereof, and their medical applications. These compounds inhibit the action of chemokines such as MIP-1&agr; and/or MCP-1 on target cells, and are useful as therapeutic and/or preventative drugs in diseases, such as atherosclerosis, rheumatoid arthritis, and the like where blood monocytes and lymphocytes infiltrate into tissues.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.