Process for the preparation of fluorobenzyl derivatives
US6452056B1 · kind B1 · utility
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8Claims
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Key dates
| Filing date | Feb 20, 2001 |
| Grant date | Sep 17, 2002 |
| Priority date | — |
| Expiry date | Feb 20, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C29/09
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A fluorine-containing benzonitrile derivative (formula 1) is subjected to a reduction reaction to obtain a fluorine-containing benzylamine derivative (formula 2), and the amino group in said fluorine-containing benzylamine derivative is replaced with a hydroxyl group to obtain a fluorine-containing benzyl alcohol derivative (formula 3): wherein X is a halogen atom, when m is an integer of 2 or more, each X may be the same or different, and m is an integer of from 0 to 4.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.