Collagen IV adhesion assay for intraocular lens materials
US6455318B1 · kind B1 · utility
1Cited by
22References
17Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Aug 21, 2001 |
| Grant date | Sep 24, 2002 |
| Priority date | — |
| Expiry date | Aug 21, 2021 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/78
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
A method for determining the propensity of an intraocular lens material to prevent posterior capsule opacification is disclosed. The method involves incubating replicate samples of an IOL material with collagen IV, washing off any loosely bound collagen IV. Following the washing step, one sample is counted to determine the amount of collagen IV that remains adhered to the IOL material. A second sample is further processed prior to counting by subjecting it to a desorption step and a further washing step.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.