Flavanone derivatives and composition for preventing or treating blood lipid level-related diseases comprising same
US6455577B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jan 24, 2001 |
| Grant date | Sep 24, 2002 |
| Priority date | — |
| Expiry date | Jan 24, 2021 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA23V2002/00
- WIPO fieldFood chemistry
- WIPO sectorChemistry
Abstract
A compound of formula (I) treating or preventing an elevated blood lipid level-related disease and inhibiting the activities of acyl-CoA:cholesterol-O-acyltransferase(ACAT) and 3-hydroxy-3-methylglutaryl CoA(HMG-CoA) reductase: wherein,R1 is R5 R6CO group;R2 is H or R6CO group;R3 is H, CH3, R5 or R6CO group;R4 is H, OH, OR5 or R6COO group;R5 is a C2-5 alkyl group substituted with a phenyl group optionally having one or more substituents selected from the group consisting of C1-3 alkyl, OH, Cl and NO2; a C1-5 alkyl group substituted with a naphthyl group optionally having one or more substituents selected from the group consisting of C1-3 alkyl, OH, Cl and NO2; a C10-18 alkyl; or a C10-18 alkenyl group; andR6 is a C10-18 alkenyl group; or an aryl group optionally having one or more substituents selected from the group consisting of C1-3 alkyl, OH, Cl or NO2.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.