Pentamer peptide amide, ALGPG-NH2, that inhibits viral infectivity and methods of use thereof

US6455670B1 · kind B1 · utility

Assignee

• TRIPEP AB · SE

Inventors

• David van der Spoel · Uppsala, SE
• Csaba Hetényi · Uppsala, SE
• Ákos Végvári · Uppsala, SE
• Stefan Höglund · Uppsala, SE
• Jin-Lian Su · Markham, CA
• Sarah Sandin-Reneby · Stockholm, SE
• Laura Goobar-Larsson · Stockholm, SE
• Anders Vahlne · Strömstad, SE

Key dates

• Filing date: Sep 6, 2001
• Grant date: Sep 24, 2002
• Expiry date: Sep 6, 2021

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2740/16222
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to the discovery that a specific pentamer peptide amide, ALGPG-NH2, which corresponds to a viral capsid sequence, can be used to inhibit viral infection, including human immunodeficiency virus (HIV) infection. More specifically, medicaments comprising said pentamer peptide amide and methods of using said compounds for the prevention and treatment of viral infection, such as HIV infection, are provided.