Thrombin inhibitors, the preparation and use thereof

US6455671B1 · kind B1 · utility

Assignee

• Abbott Laboratories · US

Inventors

• Hans-Joachim Bohm · Schifferstadt, DE
• Stefan Koser · Ludwigshafen, DE
• Helmut Mack · Ludwigshafen, DE
• Thomas Pfeiffer · Kumhausen, DE
• Werner Seitz · Plankstadt, DE
• Hans Wolfgang Höffken · Ludwigshafen, DE
• Wilfried Hornberger · Wiesbaden, DE

Key dates

• Filing date: Dec 16, 1996
• Grant date: Sep 24, 2002
• Expiry date: Dec 16, 2016

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K38/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Compounds of the formula and the salts thereof with physiologically tolerated acids and the stereoisomers thereof, in which the substituents have the meanings stated in the description, are described. Also disclosed are intermediates for their preparation. The compounds are suitable for controlling diseases.