Process for preparation of pharmaceutically desired sertraline and sertraline analogs
US6455736B1 · kind B1 · utility
11Cited by
5References
8Claims
0Family size
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Key dates
| Filing date | Nov 3, 2000 |
| Grant date | Sep 24, 2002 |
| Priority date | — |
| Expiry date | Nov 3, 2020 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2030/8877
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Improved processes for preparation of sertraline or sertraline analogs in high enantiomeric purity centers on resolution using simulated moving bed chromatography of isomeric racemic sertraline or sertraline analogs. Resolution is effected with high enantiomeric purity, and the undesired enantiomer may be racemized and recycled to the resolution phase to avoid loss.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.