Emulsion vehicle for poorly soluble drugs
US6458373B1 · kind B1 · utility
152Cited by
30References
14Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 5, 1998 |
| Grant date | Oct 1, 2002 |
| Priority date | — |
| Expiry date | Jan 5, 2018 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S977/915
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
An emulsion of &agr;-tocopherol, stabilized by biocompatible surfactants, as a vehicle or carrier for therapeutic drugs, which is substantially ethanol free and which can be administered to animals or humans various routes is disclosed. Also included in the emulsion is PEGylated vitamin E. PEGylated &agr;-tocopherol includes polyethylene glycol subunits attached by a succinic acid diester at the ring hydroxyl of vitamin E and serves as a primary surfactant, stabilizer and a secondary solvent in emulsions of &agr;-tocopherol.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.