Bovine cells expressing adenovirus essential functions for propagation of recombinant adenoviral vectors
US6458586B1 · kind B1 · utility
2Cited by
3References
33Claims
0Family size
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Inventors
Key dates
| Filing date | Nov 1, 1999 |
| Grant date | Oct 1, 2002 |
| Priority date | — |
| Expiry date | Nov 1, 2019 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S424/813
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides cell lines capable of supporting the replication of a defective recombinant virus vector. In one aspect, bovine cell lines expressing adenovirus E1 functions are provided. The cell lines are useful for the propagation of adenovirus vectors with mutations and/or deletions in E1 and other essential regions of the adenovirus genome.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.