Substituted pyridine compounds and methods of use
US6458813B1 · kind B1 · utility
32Cited by
22References
17Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 17, 2001 |
| Grant date | Oct 1, 2002 |
| Priority date | — |
| Expiry date | Aug 17, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D471/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Selected novel substituted pyridine compounds are effective for prophylaxis and treatment of diseases, such as TNF-&agr;, IL-1&bgr;, IL-6 and/or IL-8 mediated diseases, and other maladies, such as pain and diabetes. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving inflammation, pain, diabetes, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.