Patent · US Expired

Solid preparation

US6458824B1 · kind B1 · utility

15Cited by
1References
17Claims
0Family size

Assignee

Inventors

Key dates

Filing dateSep 14, 2000
Grant dateOct 1, 2002
Priority date
Expiry dateSep 14, 2020

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P43/00
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The present invention provides a solid preparation comprising a crystal of [3-[(2R)-[[(2R)-(3-chlorophenyl)-2-hydroxyethyl]amino]propyl]-1H-indol-7-yloxy]acetic acid (Compound A), especially a crystal of Compound A having a particle size of not larger than 100 &mgr;m at the cumulative weight distribution value of 50%, and not larger than 200 &mgr;m at the cumulative weight distribution value of 95%, preferably a solid preparation having the excellent stability and the content uniformity of Compound A, which is prepared by preparing granules of the crystal of Compound A with fillers, disintegrants and binders, and then followed by mixing said granules with external excipients.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.