Crystal structure of E. coli GDP-fucose synthetase (and complexes thereof) and methods of identifying agonists and antagonists using same
US6459996B1 · kind B1 · utility
7Cited by
1References
10Claims
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Key dates
| Filing date | Aug 13, 1999 |
| Grant date | Oct 1, 2002 |
| Priority date | — |
| Expiry date | Aug 13, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N9/90
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides for crystalline GFS. The crystal structure of GFS has also been solved using such material. Models based upon such crystal structure are also provided. Methods of identifying inhibitors of GFS activity using such models are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.