Crystalline IL-6 and models of the molecular structure of IL-6
US6461604B1 · kind B1 · utility
13Cited by
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14Claims
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Key dates
| Filing date | Feb 7, 2000 |
| Grant date | Oct 8, 2002 |
| Priority date | — |
| Expiry date | Feb 7, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K14/5412
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Crystallographic and NMR solution structures of human IL-6 are reported. The invention provides models and systems incorporating such structures which are useful for identifying IL-6/IL-6 receptor interactions and for identification of agonists and antagonists of such interactions. Crystalline human IL-6 is also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.