Transdermal therapeutic system containing pergolide

US6461636B1 · kind B1 · utility

Assignee

• Schwarz Pharma Ltd. · DE

Inventors

• Christoph Arth · Düsseldorf, DE
• Andreas Kollmeyer-Seeger · Langenfeld, DE
• Stephan Rimpler · Hilden, DE
• Hans-Michael Wolff · Monheim, DE

Key dates

• Filing date: Oct 10, 2000
• Grant date: Oct 8, 2002
• Expiry date: Oct 10, 2020

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P25/16
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to a transdermal therapeutic system (TTS) for the transcutaneous administration of pergolide over several days and to a method for its manufacture without using solvents. The TTS contains a matrix mass, containing pergolide and taking the form of a layer, which contains a (meth)acrylate copolymer containing ammonio groups or a mixture of a (meth)acrylate copolymer containing amino groups and a (meth)acrylate polymer containing carboxyl groups, 10-50% by weight propylene glycol and up to 5% by weight pergolide.