Recombinant production of novel polyketides

US6461838B2 · kind B2 · utility

Assignees

• The Board of Trustees of the Leland Stanford Junior University · US
• The John Innes Institute · GB

Inventors

• Chaitan Khosla · Stanford, US
• David A. Hopwood · Norwich, GB
• Suzanne Ebert-Khosla · Stanford, US
• Robert McDaniel · Palo Alto, US
• Hong Fu · Chongqing, CN
• Camilla Kao · Palo Alto, US

Key dates

• Filing date: Jan 5, 2001
• Grant date: Oct 8, 2002
• Expiry date: Jan 5, 2021

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C40B40/00
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Novel polyketides and novel methods of efficiently producing both new and known polyketides, using recombinant technology, are disclosed. In particular, a novel host-vector system is described which is used to produce polyketide synthases which in turn catalyze the production of a variety of polyketides.