Modified polypeptide
US6461849B1 · kind B1 · utility
17Cited by
9References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 13, 1999 |
| Grant date | Oct 8, 2002 |
| Priority date | — |
| Expiry date | Oct 13, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N9/54
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to polypeptides with reduced immune response including reduced allergenicity having one or more amino acid residues being substituted with other amino acid residues and/or having coupled one or more polymeric molecules in the vicinity of the polypeptides metal binding site, a method for preparing modified polypeptides of the invention, the use of the polypeptide for reducing the immunogenicity and allergenicity and compositions comprising the polypeptide.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.