Inhibitors of proteasomal activity and production for stimulating bone growth
US6462019B1 · kind B1 · utility
65Cited by
5References
6Claims
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Key dates
| Filing date | Jul 10, 1998 |
| Grant date | Oct 8, 2002 |
| Priority date | — |
| Expiry date | Jul 10, 2018 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2500/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds that inhibit the activity of NF-&kgr;B or inhibit the activity of the proteasome or both promote bone formation and are thus useful in treating osteoporosis, bone fracture or deficiency, primary or secondary hyperparathyroidism, periodontal disease or defect, metastatic bone disease, osteolytic bone disease, post-plastic surgery, post-prosthetic joint surgery, and post-dental implantation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.