Preparation of amines

US6462236B2 · kind B2 · utility

Assignee

• BASF SE

Inventors

• Shelue Liang · Ludwigshafen, DE
• Frank Funke · Bischofswerda, DE
• Arthur Hohn · Tauberbischofsheim, DE

Key dates

• Filing date: Oct 24, 2001
• Grant date: Oct 8, 2002
• Expiry date: Oct 24, 2021

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C209/26
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Amines of the formula (I)R1R2CH—NR3R4  (I)where R1, R2, R3 and R4 are each, independently of one another, hydrogen, straight-chain or branched C1-C12-alkyl, C3-C12-cycloalkyl, C6-C10-aryl or C7-C11-aralkyl, where at least one of the radicals R1 and R2 is aryl or aralkyl whose aromatic unit is substituted by at least one halogen, are prepared by catalytic, hydrogenative amination of carbonyl compounds of the formula (II) or alcohols of the formula (III)R1—C(═O)—R2  (II)R1—CH(OH)—R2  (III)by means of nitrogen compounds of the formula (IV)HNR3R4  (IV)where R1 to R4 are as defined above, in the presence of Co- and/or Ni-containing catalysts, in the additional presence of solid acid cocatalysts and in the absence of organic sulfur compounds.