Process for the selective deprotonation and functionalization of 3-substituted benzotrifluorides
US6462240B2 · kind B2 · utility
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8Claims
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Key dates
| Filing date | Jun 14, 2001 |
| Grant date | Oct 8, 2002 |
| Priority date | — |
| Expiry date | Jun 14, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F1/02
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
3-Substituted benzotrifluorides are selectively deprotonated and functionalized in the 2-position. The selectivity is achieved by equilibrating the mixture of lithiobenzotrifluorides initially formed in the presence of a primary or secondary amine catalyst.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.